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Creating More Moments

Our science is our humanity. From the individual neuron to the entire neurodegenerative disease community, we strive to enhance our knowledge, identify research opportunities, and grow our relationships to improve the lives of people with neurodegenerative diseases and of their families.

Amylyx’s mission to one day end the suffering caused by neurodegenerative diseases began with a simple question: “Why do neurons die?” Unlike most other cells in the body that regularly die and are replaced as part of healthy function, mature neurons are normally resistant to cell death.1 However, neuronal death can be triggered when multiple stress factors are activated, a circumstance commonly seen in neurodegenerative disorders.2

Most neurodegenerative disorders have complex pathophysiology, with multiple pathways contributing to eventually cause neuronal cell death. Our focus is on understanding and targeting these drivers of neuronal cell death with the goal of reducing neuronal cell death and aspiring to create more moments that matter.

  1. Milo R, Phillips R. Rates and durations. In: Cell Biology by the Numbers. 1st ed. New York, NY: Garland Science; 2016:209-281.
  2. Chi H, et al. Int J Mol Sci. 2018;19(10):3082.

Advancing Therapeutic Potential

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