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Creating More Moments

Our science is our humanity. From the individual neuron to the entire neurodegenerative disease community, we strive to enhance our knowledge, identify research opportunities, work to improve outcomes, and support people with neurodegenerative diseases and their families.

Amylyx’ mission to one day end the suffering caused by neurodegenerative diseases began with a simple question: “Why do neurons die?” Unlike most other cells in the body that regularly die and are replaced as part of healthy function, mature neurons are normally resistant to cell death.1 However, neuronal death can be triggered when multiple stress factors are activated, a circumstance commonly seen in neurodegenerative disorders.2

Most neurodegenerative disorders have complex pathophysiology, with multiple pathways contributing to eventually cause neuronal cell death. We’re focused on understanding and targeting these pathways to reduce neuronal cell death. Through scientific exploration and innovation, we aspire to create more moments for people living with neurodegenerative diseases and their loved ones – more laughs, more hugs, more memories – because every moment matters.

  1. Milo R., Phillips R. (2016). Rates and durations. In Cell Biology by the Numbers. (1st Ed). Garland Science.
  2. Chi, H., Chang, H.-Y., & Sang, T.-K. (2018). Neuronal Cell Death Mechanisms in Major Neurodegenerative Diseases. International Journal of Molecular Sciences, 19(10).

Advancing Research in Neurodegenerative Diseases