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Advancing AMX0114 for ALS: Updates from the LUMINA Phase 1 Study
Lead Author: Lauren Kett, MD, PhD (Presenter)
Published: European Network to Cure ALS (ENCALS) 2026 Meeting
Date: June 24, 2026
Participant-Informed Design Considerations in Phase 3 LUCIDITY Trial of Avexitide for Post-Bariatric Hypoglycemia
Lead Author: Marilyn Tan, MD, FACE (Presenter)
Published: Endocrine Society’s Annual Meeting (ENDO 2026)
Date: June 15, 2026
Characterizing the Burden of Post-Bariatric Hypoglycemia in the United States
Lead Author: Colleen Craig, MD (Presenter)
Published: Endocrine Society’s Annual Meeting (ENDO 2026)
Date: June 14, 2026
AMX0035 in Wolfram Syndrome: Program Progress and Emerging Insights
Lead Author: Jamie Timmons, MD (Presenter)
Published: Wolfram Syndrome UK’s International Researcher’s Symposium
Date: June 4, 2026
Phase 2 trial of sodium phenylbutyrate and taurursodiol in Wolfram syndrome
Lead Author: Fumihiko Urano, MD, PhD
Published: The Journal of Clinical Investigation
Date: May 15, 2026
Initial Safety Findings from the Phase 1 LUMINA Trial of AMX0114 in Amyotrophic Lateral Sclerosis
Lead Author: Lauren Kett, MD, PhD (Presenter)
Published: Muscular Dystrophy Association (MDA) Clinical & Scientific Conference 2026
Date: March 11, 2026
Characterizing the CSF Biomarker Signature of Calpain-2 Activity in ALS and Its Application in the Phase 1 LUMINA Trial
Lead Author: Robert Bowser, PhD (Presenter)
Published: 36th International Symposium on ALS/MND (MNDA)
Date: December 6, 2025
A Phase 1, Multicenter, Randomized, Placebo-Controlled Multiple Ascending Dose Study to Evaluate the Safety and Tolerability of AMX0114 in Amyotrophic Lateral Sclerosis (LUMINA)
Lead Author: Sabrina Paganoni, MD, PhD (Presenter)
Published: 36th International Symposium on ALS/MND (MNDA)
Date: December 5, 2025
48-Week Results from the Phase 2, Open-Label Study Evaluating an Oral, Fixed-Dose Combination of Sodium Phenylbutyrate and Taurursodiol (PB&TURSO) in Wolfram Syndrome
Lead Author: Jamie Timmons, MD
Published: The Wolfram Syndrome UK and Snow Foundation Virtual Global Research and Trial Update
Date: November 15, 2025
LUMINA Study Update
Lead Author: Lauren Kett, MD, PhD and Sabrina Paganoni, MD, PhD (Co-Presenters)
Published: 2025 Annual NEALS Meeting
Date: October 8, 2025