Careers

At Amylyx, we’re rooted in connection

We value the connections between our company and the communities we serve, between questions and solutions, and between insights and actions. We see a path between where we are and where we need to be. Our work, our motivation, and the core values that guide us are deeply interwoven. Amylyx has assembled an experienced team ready to take action because individuals with high unmet needs and their loved ones have no time to wait.

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Our mission is powered by our people

Four Amylyx employees preparing care packages consisting of water and healthy snacks for kids attending grade school in the Greater Boston area.

Amylyx team members created snack kits that will help families in the Greater Boston area in partnership with a local organization.

Our mission is powered by our people

We know communities with high unmet needs are counting on us, and we have the drive, the integrity, and the experience to deliver. Our team brings to Amylyx collective expertise from therapeutic development through commercialization across numerous diseases, serving as a critical foundation for tackling some of medicine’s toughest challenges. Our mission would not be possible without each individual perspective within our talented team. We’re made up of determined, passionate, and empathetic people – and if that sounds like you, we’d like to meet you.

Our values create a culture of caring

Microscopic view of tau protein, colored turquoise blue to contrast against a navy blue backdrop.

Be audacious

We envision new possibilities, boldly seek untried approaches, and fearlessly innovate for people living with serious diseases with unmet needs.

Be curious

By asking the right questions, listening, and learning, we thrive in a culture of continuous improvement, driven by generously sharing knowledge, making each of us, and the company, better.

Be authentic

We have a responsibility to the communities we serve and to our colleagues to be honest and transparent in all we do. When we bring our full selves to work, we make Amylyx a place where possibility can one day turn into reality.

Be engaged

We can only understand someone's needs when we understand their journey. By deeply engaging with community members and their care providers, we know what’s needed.

Be accountable

People living with diseases with high unmet needs always come first. We have a responsibility to turn our most promising ideas into urgent action on their behalf.

Driven by People

“« Amylyx has a mission-driven, collaborative culture where people genuinely care — about the science, about each other, and about improving the lives of people living with rare diseases. I’ve felt trusted to do meaningful work alongside colleagues who approach their work with both scientific rigor and real compassion.” »

Kelly Fox, Medical Affairs

“« Authenticity is a core value at Amylyx, reflected in the honesty and transparency we bring to our co-workers, partners, and importantly, the communities we serve. It fosters a collaborative environment built on trust, enabling us to do our best work.” »

Rob Chang, Legal

“« Through my interview process years ago, I knew I was finding the right fit, not just a job. Amylyx’s Rooted in Connection^® resonated with how I’ve always approached my roles in Quality. By connecting functional teams, external partners, and communities to a common goal, that energy achieved milestones I couldn’t imagine on my own or at another company. My reasons for joining became my reason for staying at Amylyx.” »

Shannan Aschmann, Quality

“« Our company culture is deeply rooted in values like collaboration, innovation, and integrity, where people are empowered to grow, take initiative, and make a meaningful impact. It’s a supportive, inclusive environment where leadership is transparent, teams work closely, and employees genuinely enjoy working together.” »

Tapan Desai, IT

“« Few companies combine true patient centricity, rigorous science, and transparent leadership. Add to that a collaborative culture and a team of not only highly skilled professionals but also genuinely kind people, and you have something special. I’m grateful every day to be part of this incredible team.” »

Natalia Vlcek, Pharmacovigilance

“« What attracted me to Amylyx is not only our commitment to communities with high unmet needs, but our common sense of purpose and alignment to our mission. At Amylyx, we collectively possess a ‘can do’ spirit that unites our organization. The story of Amylyx is just beginning!” »

Dan Monahan, Commercial

Overview of our benefits

At Amylyx, we believe people do their best work when they feel supported – both in their careers and in their lives outside of work. That’s why we invest deeply in benefits that care for our employees and their families. Employee benefits are an important part of our Total Rewards approach, and we’re pleased to offer a comprehensive package that can be tailored to support your needs, in the way that works best for you and your family.

Our medical plans offer extensive coverage for our employees and their families with the flexibility to choose what will best suit their needs. In addition, we provide dental and vision insurance. To complement these benefits, we offer tax-advantaged accounts, including a Flexible Spending Account (FSA) or a Health Savings Account (HSA) for eligible medical expenses, Dependent Care FSA for work related child or elder care expenses, and a Limited Purpose FSA for eligible dental and vision expenses.

In addition to the competitive benefits above, we offer:

Agile Work Environment: We are hybrid-remote, and our headquarters are in Cambridge, MA.
Touchpoints Rooted in Connection: We come together as a full organization at three annual Anchor Weeks in-person and at bi-weekly Amylyx Exchange meetings. These help us connect with each other and the communities we’re serving.
Learning and Development Program: Opportunities to grow your skills at every stage of your career.
Recognition Platform: Be recognized by colleagues and leaders for the great work you do -- beyond the day-to-day.
Flexible Paid Time Off: Paid time off designed with flexibility for vacation, personal needs, school events, or appointments.

Financial Wellbeing: A 5% 401(k) employer contribution as you work toward your retirement goals.
Employee Assistance Program: Access to mental health support, work-life solutions, financial resources, and legal guidance.
Paid Parental Leave: Ability to take time off and connect with your new child.
Mobile Reimbursement: Monthly cell phone reimbursement to stay connected.

At Amylyx, we’re rooted in connection

At Amylyx, we’re rooted in connection

Our mission is powered by our people

Our mission is powered by our people

Be audacious

Be curious

Be authentic

Be engaged

Be accountable

Driven by People

“« Authenticity is a core value at Amylyx, reflected in the honesty and transparency we bring to our co-workers, partners, and importantly, the communities we serve. It fosters a collaborative environment built on trust, enabling us to do our best work.” »

“« What attracted me to Amylyx is not only our commitment to communities with high unmet needs, but our common sense of purpose and alignment to our mission. At Amylyx, we collectively possess a ‘can do’ spirit that unites our organization. The story of Amylyx is just beginning!” »

Overview of our benefits

Beyond the job description