Our beginnings were defined by an unconventional approach to making a difference. It’s a belief that drives our work forward, strengthens our connections and continues to push the boundaries of what’s possible. We are not delegators, procrastinators or nay-sayers. We’re a group of get-it-done problem solvers who never hesitate to question the obvious.

Working At Amylyx

Amylyx is a place where you can apply your curiosity and experience in ways you have never done before.  We thrive in an environment that focuses on different perspectives, finding new ways to solve common problems, and learning from collective experiences. Every day we are inspired by our patients, families, and the medical community to relentlessly pursue the treatments they need.

We are looking for mission-driven builders and collaborative self-starters who can roll their sleeves up in the interest of making a difference for our patients and each other. If that sounds like you, let’s talk.


We care deeply about the people with whom we work and have structured our benefits to connect them with support in every facet of their lives. Because when you’re at your best, we’re at ours.

  • Flexible work environment

    We want to ensure Amylyx is an organization that allows you to do your best work, wherever and whenever that is. That’s why each of our employees has the opportunity to telecommute in a way that works best for all of us.

  • Discretionary time off

    We think it’s important for team members to take time off when they need it. We offer uncapped time off with no set number of vacation days.

  • Comprehensive healthcare coverage

    Our programs ensure you have robust coverage. We offer a PPO (Preferred Provider Organization) medical plan and an HMO (Health Maintenance Organization).  Our PPO plan is paired with an HSA (Health Savings Account) in which Amylyx contributes 50% of the PPO deductible. We also offer dental benefits for our employees and their families.

  • 100% Company Paid Life and Disability Insurance

    We provide full coverage for life insurance and short- and long-term disability coverage to help care for employees and families.

  • Other Benefits
    • Paid Parental Leave
    • Employee Assistance Program
    • Commuter Benefits

Our Values

Icon: Person

Be Audacious

Patients are our true north; we envision new possibilities, boldly seek untried approaches and fearlessly innovate for them.

Icon: Question mark

Be Curious

By asking the right questions, listening and learning, we thrive in a culture of continuous improvement, driven by generously sharing knowledge, making each of us, and the company, better.

Icon: Hand Raised

Be Engaged

We can only understand patients’ needs when we understand their journey. By deeply engaging the patient and care provider communities, we know what’s needed.

Icon: Handshake

Be Accountable

Patients are waiting; they come first, and we have a responsibility to turn our most promising ideas into urgent action on their behalf.

Icon: Heart

Be Authentic

When we genuinely care about the work we do and the people with whom we work, we make Amylyx a place where breakthroughs for patients are possible.

Open Positions


If you’re here, our mission is most likely aligned with yours. Please feel free to reach out with any questions or requests for information.

Contact Us

Pegasus Alzheimer’s Trial

PEGASUS is a 3:2 randomized, double-blind, multi-center, placebo-controlled trial evaluating the safety, tolerability and activity of AMX0035 in patients with late mild cognitive impairment or early dementia due to Alzheimer’s disease over 24 weeks.

More Information

Listen to Josh Cohen, Co-CEO and Co-Founder and Justin Klee, Co-CEO and Co-Founder talk about Amylyx' origin story and hope for the future for ALS and Alzheimer's disease patients.

Listen to Podcast