Careers

We are seeking a Clinical Research Scientist for neurodegenerative indications with experience in managing multidisciplinary drug development projects. The successful candidate will interact within a multi-disciplinary, matrix work group ensuring that clinical and scientific issues are appropriately considered in the development and execution of individual clinical studies and overall clinical development plans. You will be involved in operationalizing studies, monitoring data in real time to ensure the integrity of the study, proactively identifying issues in the conduct of trials, and in medical review and analysis of data for the purposes of both data cleaning and interpretation for regulatory documents and publications.

Amylyx is seeking an experienced, collaborative, and highly motivated clinical development physician to join our team dedicated to developing treatments to slow the progression of neurodegenerative diseases including ALS and Alzheimer’s disease. Reporting directly to the Chief Medical Officer you will build and lead a team of clinical development professionals within the global neurology franchise. As a medical and clinical expert, you will provide mentoring to members of the Amylyx team.

Amylyx is headquartered in Cambridge, Massachusetts. This position can be based in Cambridge or remote.

Amylyx is seeking a highly collaborative Executive Assistant to support members of the Commercial Leadership Team. The role includes general administrative duties as well as project-based work in support of multiple functional areas. We are seeking to hire an individual with the ability to exercise good judgement in a variety of situations, strong written and verbal communication, administrative and organizational skills, and the ability to maintain a realistic balance among multiple deliverables and priorities. This role will report to the Global Head of Commercial/Chief Commercial Officer and support a team of both remote and Cambridge based employees. This position requires 2 – 3 days per week on site in the Cambridge office.

Amylyx is seeking a Medical, Legal, Regulatory Review (MLR) & Marketing Operations Manager, who will manage all aspects of the Medical, Legal, Regulatory (MLR) review committee, along with print, fulfillment, and proofreading. This role serves as the connection between marketing strategies and program execution. S/he will interface with all levels, partnering cross functionally with teams including Marketing, Sales, Market Access, Sales Training, Regulatory, Medical, Legal and Compliance teams, as well as external agency partners.

The MLR Marketing Operations Manager will own the MLR performance dashboard for leadership review. Reporting directly to the Head of Commercial Operations & Data Management, this highly visible role will have the rare opportunity to build the Marketing Operations function from the ground up as we prepare to launch Amylyx’s first commercial therapy.

The ALS Brand Lead is a critical and visible leader within the organization. Responsible for developing US engagement strategies through analysis of insights and partnerships with cross-functional stakeholders. Utilizing the strategic direction to create and execute initiatives ensuring a successful launch that maximizes brand awareness. Initially this role will also support Canadian launch efforts.

Reporting to the Head of Global Marketing, this role will require the ability to collaborate and contribute to projects across the organization. Leveraging insights learned in collaboration with market insights, analytics, and global marketing to drive the US & Canadian strategic plans and execution.

Amylyx Pharmaceuticals is searching for a Head of HR Business Partnering to join our team. In this newly created role, you will be a key member of the HR Leadership Team, partnering with the CHRO, Head of Talent Acquisition, Head of Total Rewards and HRIS and Head of EUMEA HR to design and implement HR strategies and programs to support a growing, dynamic, entrepreneurial culture.

We seek a creative thought leader who can balance the need to be a strategic consultative partner with a roll-up-your-sleeves attitude. You will focus on partnering with leaders to drive the business strategy, utilizing talent insights to drive business outcomes and create leverage as we address global, regional, and local needs in an enterprise-wide, scalable manner. Working collaboratively across the organization, you will lead the development of new talent initiatives that drive engagement, and support individual and team performance while strengthening our culture and community. As Amylyx expands globally, you will collaborate with colleagues from around the world to develop strategies and share best practices.

In this new role you will be responsible for leading the IT organizations strategy, implementation, and support for information asset management within Amylyx. This responsibility will include a range of activities within the information technology organization including project management, developing, and maintaining procedures to ensure Amylyx has a stable, robust, and scalable Data Management environment to support the changing business needs. This position will encompass many activities including managing data services providers; evaluating new applications; implementing approved solutions that will help propel and support the business goals; refining existing solutions that are currently in place and managing the day to day needs of each of the existing solutions. This is a critical role on the Information Technology team.

In this role, you will be responsible for leading the IT organizations strategy, implementation, and support for all business systems (Commercial, G&A, Clinical, R&D, Supply chain and Quality) within Amylyx. This responsibility will include a range of activities within the information technology organization including project management, developing, and maintaining procedures to ensure Amylyx has a stable, robust, and scalable set of applications to support international growth and evolving business needs. This position will encompass many activities including evaluating new applications; implementing approved solutions that will help propel and support the business goals; refining existing solutions that are currently in place and managing the day to day needs of each of the existing solutions. This is a critical and highly visible role on the Information Technology team.

Amylyx is growing as we advance AMX 0035 on an international scale. With plans to launch our drug for ALS in Canada, the EU and US, having strong legal and compliance expertise will be key to our success. At Amylyx our focus is on providing innovative treatments for patients and their families. In this role you will help drive this mission and define how we support our patients in a meaningful and compliant way.

As Head, Global Compliance you will provide leadership and vision, as well as in-depth day-to-day legal and compliance guidance on various business activities including research and development initiatives, clinical trials, medical affairs, sales and marketing, field-based activities of medical and commercial personnel, grants, HCP engagements, privacy and GDPR, Transparency & Disclosure, FCPA and third-party due diligence, at all stages of product development, including preparing for the company’s first product launch in Canada, EU and US.

Our Medical Leads (MLs) are field-based, scientific, medical experts. They are an extension of Amylyx’s medical affairs department in the field to build and facilitate strategic peer to peer relationships with key Health Care Providers (HCPs). In this role you will be providing credible and unbiased scientific information, identifying, and executing strategic medical affairs projects and supporting home office medical activities.

Amylyx is seeking a Head, Global Patient & Professional Advocacy who will develop, maintain and execute a global patient and professional advocacy strategy, including working with regional leads to adapt the strategy as needed based on local needs and guidelines for engagement. By leading collaborations and communications with global patient advocacy and professional groups externally, this position will help ensure that patient and professional group perspectives inform decision making and communications. This role collaborates cross functionally with Commercial, Corporate Communications and other colleagues responsible for patient and professional organization facing initiatives to create and implement a seamless, coordinated plan. This position will report to the Global Head of Medical Affairs.

Our Medical Leads are field-based, scientific, medical experts. They are an extension of Amylyx’s Canadian and global medical affairs departments. They work to build and facilitate strategic peer to peer relationships with key Health Care Providers (HCPs) and Stakeholders. In this role, you will be providing credible and unbiased scientific information, identifying, and executing strategic medical affairs projects and supporting home office medical activities. This role will also require seamless cross functional collaboration with commercial colleagues. This position, in conjunction with colleagues from commercial, forms the territory team that works hand in hand on key territory projects.

Reporting to the General Manager of Canada, the Head of Medical Affairs in Canada will be responsible for the development of the country’s Medical strategy and programs that support the successful commercialization of all Amylyx therapies in Canada. In this role, you will be recognized as a leader in our newly created, centralized Canadian Leadership Team and will have deep ties into the Global Medical Affairs function based in Cambridge, Massachusetts.

The Medical Affairs Head will bring strong leadership qualities, high levels of cross-functional collaboration and the ability to influence across all levels of the organization. He/she will be entrepreneurial in approach to building an organization and finding solutions for business opportunities and challenges.

The incumbent will be a strategic thinker with the ability to execute in a dynamic organization, which is rapidly moving towards commercialization. Passion for the patient community and commitment to patient advocacy are paramount for this position.

The Head, Clinical Quality Assurance oversees all aspects of GCP QA activities internally at Amylyx as well as Investigator Sites and CROs and GCP Vendors. In this role you will lead or oversees GCP activities and lead GCP inspection readiness. The successful candidate will ensure high quality execution of clinical trials from first in human through commercial marketing authorization. In this role you will manage cross functional relationships with internal and external stakeholders and be the Lead Quality Assurance representative on clinical teams for ongoing clinical trials. This newly created role is a high visibility position with great impact potential.

Amylyx is seeking a Head of QMS who will be responsible for developing, maintaining, and executing Quality Management Systems (QMS) and processes to ensure GxP compliance. We are looking for a hands-on individual that can partner with internal departments to develop and support the Documentation Management System (DMS), Learning Management System (LMS) and Quality Management System (QMS) for Deviations, CAPAs, change control and complaints including process improvement implementations that meet business and regulatory requirements. The individual will also be responsible for complaints, APQR, Recalls and Quality oversite of Computer System Validation. The individual will lead inspection readiness activities to assure Amylyx is inspection ready at all times.

As Amylyx continues to grow and prepare to bring our medicines to patients, we are expanding the Quality function in all areas, in particular oversight of our third-party laboratories and stability programs. If you are passionate about Quality and drug development, this is an excellent opportunity for you! In this newly created role, the Lead of Quality Control will provide quality oversight of bulk drug product and finished drug product testing and stability programs to expand into US, Canadian and International markets. Responsibilities may also include review of manufacturing, packaging, labeling and distribution documents for clinical and marketed product. You will provide support on Quality Management Systems within GMP operations for internal implementation as well as integration with contracted partners. As the Quality Control expert, you are accountable for ensuring all company, regional, and global GMP and GDP standards and regulations are met, and that the GMP Quality department performs to a standard that ensures the quality of products and materials produced by our contracted partners. As we prepare for global commercialization, you will support the implementation and operation of commercial quality control systems.

Reporting to the Head, Global Regulatory Affairs, the successful candidate holds significant responsibility for regulatory strategy and operations on identified projects, ensuring that Company products comply with and meet regulatory requirements. You will work closely with internal and external teams from Supply Chain, Quality, Contract Manufacturing Organizations, as well as external consultants to advance the company’s portfolio. Responsibilities include representation on project teams, coordination and preparation of regulatory submissions, license renewals and annual registrations/updates. Recommends changes to ensure continued compliance with applicable regulations.