Careers

Reporting to the Head of Global Clinical Operations, you will be responsible for managing US and international clinical studies in ALS and Alzheimer’s disease. The ideal candidate will be a seasoned clinical operations trial lead, comfortable working independently, have experience managing cross-functional activities internally and externally, strong vendor management skills, experience managing full-service CROs, a proactive problem-solver, proficient verbal and written communication. Experience working on global pivotal clinical studies in a small fast-paced company environment is a plus.

The Head of Biometrics will be a senior member of the Clinical Development Leadership Team (CDLT), and work with a high-performing cross-functional team. In this newly created position, you will have the opportunity to build and lead the Biometrics function at Amylyx. As the first person in biometrics, this will be a hands-on role partnering with external consultants and managing vendors.

The ideal candidate will have significant experience in all phases of new drug development including a track record of successful regulatory interactions on accelerated timelines.

We are seeking a Lead, Clinical Research Scientist for neurodegenerative indications with experience in managing multidisciplinary drug development projects. The successful candidate will interact within a multi-disciplinary, matrix work group ensuring that clinical and scientific issues are appropriately considered in the development and execution of individual clinical studies and overall clinical development plans. You will be involved in operationalizing studies, monitoring data in real time to ensure the integrity of the study, proactively identifying issues in the conduct of trials, and in medical review and analysis of data for the purposes of both data cleaning and interpretation for regulatory documents and publications.

Amylyx is seeking an experienced, collaborative, and highly motivated clinical development physician to join our team dedicated to developing treatments to slow the progression of neurodegenerative diseases including ALS and Alzheimer’s disease. Reporting directly to the Chief Medical Officer you will build and lead a team of clinical development professionals within the global neurology franchise. As a medical and clinical expert, you will provide mentoring to members of the Amylyx team.

Reporting to the Head of Global Clinical Operations, you will be responsible for managing clinical studies in ALS and Alzheimer’s disease. The ideal candidate will be a seasoned clinical operations trial lead, comfortable working independently, have experience managing cross-functional activities internally and externally, strong vendor management skills, experience managing full-service CROs, a proactive problem-solver, proficient verbal and written communication. Experience working on global pivotal clinical studies in a small face-paced company environment is a plus.

As a key member of the Patient Services and Commercial Distribution team, the North America (NA) Head of Patient Services and Pharmacy Distribution will be responsible for leading the development and execution of the Patient Services and pharmacy distribution strategy for Amylyx Pharmaceuticals. The successful Patient Services outcome is streamlined and transparent coverage resulting in unimpeded and timely patient access to therapy with a focus on conversions and adherence.

This individual will drive Amylyx’s patient services concept and value proposition while aligning with brand strategy and seeking out innovative and new approaches to patient services through market research and cross functional collaboration. This individual will also have responsibility for helping create Amylyx’s distribution concept, value proposition, and managing specialty pharmacy vendor(s). The successful Channel outcome is a channel and distribution strategy that will economically provide seamless product distribution, complete data collection and guarantee product integrity/pedigree. Success will be driven through alignment of Amylyx strategies with defined critical success factors, key performance indicators, while supporting business tactics for AMX-0035. This individual will foster strong partnerships with other cross functional teams such as Sales, Marketing, Legal, Supply Chain, Field Reimbursement and Sales/Marketing Operations.

The Head of Global Commercial Training and Development will play a critical role in building and leading the vision, structure, organizational capabilities, and operating model for commercial learning and development at Amylyx. In this role you will partner with fellow members of the Global Amylyx leadership team to include, General Managers, Marketing leads, Commercial Analytics and Medical Affairs leads.

The successful candidate will be responsible for building the commercial training and development function, developing training strategy, and directing the implementation. Leading with our values, one of which is curiosity and being a learning environment, this role will establish the concepts of learning, development, and continual improvement across the organization globally.

Amylyx is seeking a finance professional with strong analytical and communication skills to lead the Financial Planning & Analysis function and provide support on business development initiatives.

This position offers a unique opportunity to report directly into a seasoned and experienced CFO and have direct access to the founding Co-CEOs and the Amylyx leadership team. You will be a key business partner for our senior leadership team, shaping corporate strategy as well as business planning and decision making for commercial operations, manufacturing/supply chain, and R&D. New product planning and long-range valuation are critical elements to our success and responsibilities will be commensurate with your expertise and demonstrated success. We are focused on potential and expect the candidate to grow to be an integral part of the Finance leadership team.

We are seeking an exceptionally talented and analytical finance professional that has developed integrated budgets, managed scenario-based forecasts, and conducted insightful analyses. Experience in the biotechnology industry is strongly preferred.

In this role you will be responsible for a range of activities within accounting and financial reporting including, developing and maintaining accounting principles, practices, and procedures to ensure accurate and timely financial statements. This position will encompass many accounting activities including general ledger preparation, financial reporting, year-end, tax and audit preparation, and will provide support on budget, forecasting and long-term financial planning activities. This is a highly visible role on the finance team – you will provide internal guidance and partner with cross functional teams, as well as external partners.

The Head of Total Rewards and HR Systems is a newly created role, responsible for leading and managing the design, implementation, communication, and ongoing evaluation of our total rewards strategy and programs.  Additionally, you will be responsible for building and executing a holistic HR systems roadmap that supports data driven decision making, automates transactional work while effectively providing seamless digital interactions for employees.

You will ensure that Amylyx’s compensation, benefits, equity, and other rewards programs are forward-thinking and competitive, support the delivery of our desired employee experience and are aligned with the Company’s culture and business strategy.  You must be comfortable working in an entrepreneurial environment at both the strategic and tactical levels, thinking longer-term while rolling up your sleeves to execute the details.

Amylyx is seeking a Head, Global Medical Affairs Operations to lead the planning and tactical execution of global medical affairs plans across pre-clinical, clinical stage and/or marketed programs. This individual will be responsible for establishing strategies and processes to ensuring synergies across programs and territories and will proactively highlight risks, timeline delays and other issues and ensure development of proper contingency plans. This position reports to the Vice President and Global Head of Medical Affairs.

The Lead, GCP Quality Assurance performs GCP QA activities related to his/her assigned clinical trials/studies and to general Amylyx quality, compliance, and inspection readiness activities. This role provides direct quality oversight and consultation to clinical teams and interacts with cross-functional internal and external stakeholders to assure the quality of Amylyx-sponsored clinical trials/studies.

Amylyx is seeking a Head of Quality Compliance who will be responsible for developing, maintaining, and executing Quality Management Systems (QMS) and processes to ensure GxP compliance. We are looking for a hands-on individual that can partner with internal departments to develop and support the Documentation Management System (DMS), Learning Management System (LMS) and Quality Management System (QMS) process improvement implementations that meet business and regulatory requirements. In this role, you will lead inspection readiness activities to assure Amylyx is inspection ready at all times. You will also be responsible for supplier oversight and audit execution.

The Global Head, Logistics & Trade Compliance leads a team responsible for the clinical and commercial supply chain shipping and distribution and execution for Amylyx’ s clinical supply and to-be-marketed products. Reporting to the Head of External Supply, the leader in this role is responsible for strategic leadership and operational execution of all activities and relationships required to ensure the timely and compliant delivery of product for clinical and commercial distribution. As a key leader in the rapidly growing Supply Chain organization, this role leads and impacts end-to-end supply chain activities from Phase I clinical studies through commercialization to meet the primary goal of fulfilling and delivering to customers. The leader also sets strategic direction and vendor relationship for all transportation supporting all GXP operations.

In this role you will provide technical leadership and serve as the process owner for Amylyx’s lead compound, AMX-3500. This position will support assets throughout the lifecycle including process development, optimization, scale-up, validation, and continuous improvement. You will be the primary technical lead for process validation, process improvements, technical transfers, and ongoing manufacturing technical support. Working in conjunction with a cross-functional team, you will participate in the long-term CMC Asset strategic plan development and ultimate implementation of activities to meet long range forecasts, reduce supply risks, improve processes, reduce COGS, and support global expansion.  This role reports to the Head, CMC Asset Operations Management.