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Preliminary Experience With Sodium Phenylbutyrate and Taurursodiol in a United States Expanded Access Program

Lead Author: Machelle Manuel, PhD

Published: Northeast ALS Consortium Annual Meeting (NEALS)

Date: October 4 - 6, 2023

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Real-World Experience and Strategies to Enhance the Palatability of the Combination Sodium Phenylbutyrate and Taurursodiol for the Treatment of Amyotrophic Lateral Sclerosis

Lead Author: Jamie Timmons, MD

Published: Northeast ALS Consortium Annual Meeting (NEALS)

Date: October 4 - 6, 2023

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Update on AMX0114: An Antisense Oligonucleotide Targeting Calpain-2, a Critical Effector of Axonal Degeneration

Lead Author: Jamie Timmons, MD

Published: Northeast ALS Consortium Annual Meeting (NEALS)

Date: October 4 - 6, 2023

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Characterization of the Enrolled Population in the Phase 3 PHOENIX Trial in Amyotrophic Lateral Sclerosis: Preliminary Results

Lead Author: Leonard van den Berg (Presenter)

Published: European Network to Cure ALS (ENCALS)

Date: July 12 - 14, 2023

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Efficacy of Sodium Phenylbutyrate and Ursodoxicoltaurine Combination in Transgenic Mice Displaying Progressive Motor Neuron Degeneration Phenotype

Lead Author: Jamie Timmons (Presenter)

Published: European Network to Cure ALS (ENCALS)

Date: July 12 - 14, 2023

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Effect of an Oral, Fixed-Dose Combination of Sodium Phenylbutyrate and Taurursodiol on Long-Term Tracheostomy/Ventilation-Free Survival and Hospitalization in Amyotrophic Lateral Sclerosis: Final Results From CENTAUR

Lead Author: Janelle Schafer (Presenter)

Published: International Society for Pharmacoeconomics and Outcomes Research (ISPOR)

Date: May 6 - 10, 2023

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Development and Preclinical Assessment of AMX0114: an Antisense Oligonucleotide Targeting Calpain-2, a Critical Effector of Axonal Degeneration

Lead Author: Joshua Cohen, Co-CEO and Co-Founder, Amylyx Pharmaceuticals

Published: Muscular Dystrophy Association (MDA)

Date: March 19 - 22, 2023

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Expanded Access to Sodium Phenylbutyrate and Taurursodiol Coformulation in Amyotrophic Lateral Sclerosis: Updates and Initial Learnings

Lead Author: Sandy Morris, BA, BS, MBA & Philip Green, BS (Presenter)

Published: International Symposium on ALS-MND (MNDA)

Date: December 5 - 9, 2022

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Independent Expert Review of Cardiac Adverse Events and Electrocardiographic Abnormalities and Parameters in a Phase 2 Trial of Sodium Phenylbutyrate and Taurursodiol in Amyotrophic Lateral Sclerosis (CENTAUR)

Lead Author: Shide Badri, MD, MPH

Published: International Symposium on ALS-MND (MNDA)

Date: December 5 - 9, 2022

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Update on an International Phase 3 Trial Evaluating Sodium Phenylbutyrate and Taurursodiol in Amyotrophic Lateral Sclerosis (PHOENIX)

Lead Author: Leonard H. van den Berg, MD, PhD

Published: International Symposium on ALS-MND (MNDA)

Date: December 5 - 9, 2022

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