Skip to main content

ORION: A Global Phase 2b/3, Randomized, Double-Blind, Placebo-Controlled Trial of AMX0035 in Progressive Supranuclear Palsy (A35-009)

Lead Author: Anne-Marie Wills, MD

Published: International Parkinson and Movement Disorder Society

Date: October 1, 2024

Read more (opens new window)

Biological Effects of Sodium Phenylbutyrate and Taurursodiol in Alzheimer's Disease

Lead Author: Steven E. Arnold

Published: Alzheimer’s & Dementia: Translational Research & Clinical Interventions, a journal of the Alzheimer’s Association

Date: August 9, 2024

Read more (opens new window)

Preclinical Development of AMX0114, an Antisense Oligonucleotide Targeting Calpain-2

Lead Author: Evan Mizerak (Presenter)

Published: Oligonucleotides for CNS Summit

Date: July 10, 2024

Read more (opens new window)

Learnings from the CENTAUR and PHOENIX Trials: Biomarker Results

Lead Author: Sabrina Paganoni, MD, PhD (Presenter)

Published: European Network to Cure ALS (ENCALS) Meeting 2024

Date: June 17 - 20, 2024

Read more (opens new window)

Results From the Global Phase 3 Trial Evaluating Sodium Phenylbutyrate and Ursodoxicoltaurine in ALS

Lead Author: Leonard H. van den Berg, MD, PhD, and Sabrina Paganoni, MD, PhD (Presenters)

Published: European Network to Cure ALS (ENCALS) Meeting 2024

Date: June 17 - 20, 2024

Read more (opens new window)

Updates on Development of AMX0114: An Antisense Oligonucleotide Inhibitor of Calpain-2, a Critical Effector of Axonal Degeneration

Lead Author: Lauren Kett, MD, PhD (Presenter)

Published: European Network to Cure ALS (ENCALS) Meeting 2024

Date: June 17 - 20, 2024

Read more (opens new window)

Understanding Treatment Barriers and Adherence Among People Living with Amyotrophic Lateral Sclerosis in Real World Clinical Practice

Lead Author: Genevieve Matte, MDCM, FRCP (Presenter)

Published: 2024 Canadian Neurological Sciences Federation (CNSF) Congress

Date: May 20 - 26, 2024

Read more (opens new window)

Assessment of AMX0114, An Antisense Oligonucleotide Targeting Calpain-2, in Multiple Models of Axonal Degeneration

Lead Author: Evan Mizerak (Presenter)

Published: TIDES USA | Oligonucleotide & Peptide Therapeutics

Date: May 14 - 17, 2024

Read more (opens new window)

Results From a Global Phase 3 Trial Evaluating an Oral, Fixed-Dose Combination of Sodium Phenylbutyrate and Taurursodiol in Amyotrophic Lateral Sclerosis

Lead Author: Leonard H van den Berg, MD, PhD (Presenter)

Published: American Academy of Neurology Annual Meeting 2024

Date: April 13 - 18, 2024

Read more (opens new window)

ORION: A Global, Phase 3, Randomized, Double-Blind, Placebo-Controlled Trial of AMX0035 in Progressive Supranuclear Palsy

Lead Author: Günter Höglinger, MD (Presenter)

Published: AD/PD 2024 International Conference on Alzheimer’s and Parkinson’s Diseases (AD/PD)

Date: March 5 - 9, 2024

Read more (opens new window)