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Results From the Global Phase 3 Trial Evaluating Sodium Phenylbutyrate and Ursodoxicoltaurine in ALS
Lead Author: Leonard H. van den Berg, MD, PhD, and Sabrina Paganoni, MD, PhD (Presenters)
Published: European Network to Cure ALS (ENCALS) Meeting 2024
Date: June 17 - 20, 2024
Updates on Development of AMX0114: An Antisense Oligonucleotide Inhibitor of Calpain-2, a Critical Effector of Axonal Degeneration
Lead Author: Lauren Kett, MD, PhD (Presenter)
Published: European Network to Cure ALS (ENCALS) Meeting 2024
Date: June 17 - 20, 2024
Understanding Treatment Barriers and Adherence Among People Living with Amyotrophic Lateral Sclerosis in Real World Clinical Practice
Lead Author: Genevieve Matte, MDCM, FRCP (Presenter)
Published: 2024 Canadian Neurological Sciences Federation (CNSF) Congress
Date: May 20 - 26, 2024
Assessment of AMX0114, An Antisense Oligonucleotide Targeting Calpain-2, in Multiple Models of Axonal Degeneration
Lead Author: Evan Mizerak (Presenter)
Published: TIDES USA | Oligonucleotide & Peptide Therapeutics
Date: May 14 - 17, 2024
Results From a Global Phase 3 Trial Evaluating an Oral, Fixed-Dose Combination of Sodium Phenylbutyrate and Taurursodiol in Amyotrophic Lateral Sclerosis
Lead Author: Leonard H van den Berg, MD, PhD (Presenter)
Published: American Academy of Neurology Annual Meeting 2024
Date: April 13 - 18, 2024
ORION: A Global, Phase 3, Randomized, Double-Blind, Placebo-Controlled Trial of AMX0035 in Progressive Supranuclear Palsy
Lead Author: Günter Höglinger, MD (Presenter)
Published: AD/PD 2024 International Conference on Alzheimer’s and Parkinson’s Diseases (AD/PD)
Date: March 5 - 9, 2024
Findings From a Pharmacokinetic and Pharmacodynamic Study of Sodium Phenylbutyrate and Taurursodiol in Participants With Amyotrophic Lateral Sclerosis
Lead Author: James Wymer, MD (Presenter)
Published: 2024 MDA Clinical & Scientific Conference (MDA)
Date: March 3 - 6, 2024
Next Steps in Development for AMX0114: An Antisense Oligonucleotide Targeting Calpain-2, a Critical Effector of Axonal Degeneration
Lead Author: Joshua Cohen
Published: 2024 MDA Clinical & Scientific Conference (MDA)
Date: March 3 - 6, 2024
A Joint Model for Assessing Mortality-Adjusted Progression (MAP) in Amyotrophic Lateral Sclerosis: Application to Clinical Trials of Sodium Phenylbutyrate and Taurursodiol
Lead Author: Ruben van Eijk
Published: International Symposium on ALS/MND (MNDA)
Date: December 6 - 8, 2023
Effect of Sodium Phenylbutyrate and Taurursodiol on Plasma Concentrations of Neuroinflammatory Biomarkers in Amyotrophic Lateral Sclerosis: Results From the CENTAUR Trial
Lead Author: Robert Bowser, PhD & Jiyan An
Published: Journal of Neurology, Neurosurgery and Psychiatry
Date: December 2, 2023